Pharmacogenetic Dose Modeling Based on CYP2C19 Allelic Phenotypes
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DOI: 10.3390/pharmaceutics14122833
Abstract: Pharmacogenetic variability in drug metabolism leads to patient vulnerability to side effects and to therapeutic failure. Our purpose was to introduce a systematic statistical methodology to estimate quantitative dose adjustments based on pharmacokinetic differences in… read more here.
Keywords: based cyp2c19; cyp2c19 allelic; modeling based; dose modeling ... See more keywords