Effects of CYP2C19*17 genetic polymorphisms on plasma and saliva concentrations of diazepam in patients with alcohol withdrawal syndrome
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DOI: 10.1097/ypg.0000000000000306
Abstract: Introduction Diazepam is one of the most commonly prescribed tranquilizers for the therapy of alcohol withdrawal syndrome (AWS). However, diazepam therapy often turns out to be ineffective, and some patients experience dose-dependent adverse drug reactions.… read more here.
Keywords: alcohol withdrawal; cyp2c19 genetic; genetic polymorphisms; withdrawal syndrome ... See more keywords
Effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of lacosamide in Korean patients with epilepsy
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DOI: 10.1111/epi.17399
Abstract: Many pharmacokinetic studies of lacosamide (LCM) have been reported, but no large‐scale clinical study has been conducted on genetic polymorphisms that affect the metabolism of LCM. Therefore, we designed a pharmacogenetic study of LCM to… read more here.
Keywords: pharmacokinetics lacosamide; genetic polymorphisms; cyp2c19 genetic; polymorphisms pharmacokinetics ... See more keywords