Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro
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DOI: 10.1159/000475598
Abstract: Aims: CYP2C19 is an important member of the cytochrome P450 enzyme superfamily. We recently identified 31 CYP2C19 alleles in the Han Chinese population. The aim of this study was to assess the catalytic activities of… read more here.
Keywords: cyp2c19 variants; vitro; effects cyp2c19; cyp2c19 ... See more keywords
The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro
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DOI: 10.2147/idr.s179078
Abstract: Background CYP/CYP450 2C19 (CYP2C19) is a highly polymorphic enzyme and exhibits individual differences in metabolic activity. The purpose of this research was mainly to explore the catalytic activities of 30 CYP2C19 variants on the substrate… read more here.
Keywords: p450 2c19; metabolism; cyp2c19 variants; effects cytochrome ... See more keywords