Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
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DOI: 10.1124/dmd.116.074583
Abstract: Predicting age-specific metabolism is important for evaluating age-related drug and chemical sensitivity. Multiple cytochrome P450s and carboxylesterase enzymes are responsible for human pyrethroid metabolism. Complete ontogeny data for each enzyme are needed to support in… read more here.
Keywords: age dependent; age; cyp2c8; cyp2c8 cyp1a2 ... See more keywords