Articles with "cyp2c9 abcb1" as a keyword



Modeling the Influence of CYP2C9 and ABCB1 Gene Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Losartan

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Published in 2025 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics17070935

Abstract: Background/Objectives: Hypertension is a pathological condition characterized by elevated systolic and/or diastolic blood pressure. A range of pharmacotherapeutic agents are available to treat this condition and prevent complications, including the angiotensin II AT1-receptor blocker losartan.… read more here.

Keywords: pharmacodynamics losartan; cyp2c9 abcb1; pharmacokinetics pharmacodynamics; abcb1 gene ... See more keywords