Effect of CYP2D6*4, CYP2D6*10 polymorphisms on the safety of treatment with timolol maleate in patients with glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2022-0117
Abstract: Abstract Objectives Timolol maleate is used for the treatment of glaucoma and metabolized by cytochrome CYP2D6 in the liver. The aim of this study was the evaluation of the influence of CYP2D6*4 and CYP2D6*10 gene… read more here.
Keywords: glaucoma; timolol maleate; cyp2d6 cyp2d6; cyp2d6 ... See more keywords
The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.940510
Abstract: Aims: The CYP2D6*41 variant is the second or third frequent reduced function allele in Chinese with a frequency of around 3–4%, while it is the major reduced function allele in Indians, Saudi Arabians and Caucasians… read more here.
Keywords: cyp2d6 cyp2d6; cyp2d6; impact cyp2d6; plasma ... See more keywords