Pharmacogenetic relevant polymorphisms of CYP2C9, CYP2C19, CYP2D6, and CYP3A5 in Bhutanese population
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DOI: 10.1515/dmpt-2019-0020
Abstract: Abstract Background Marked differences among genotype frequencies (Caucasians, Asians, and Africans) have been observed in cytochrome P450 (CYP) genes. Data on the frequency of pharmacogenetic relevant polymorphisms in Bhutanese population is absent. This study aimed… read more here.
Keywords: pharmacogenetic relevant; cyp2d6 cyp3a5; relevant polymorphisms; bhutanese population ... See more keywords
Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients
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DOI: 10.3389/fmed.2021.683498
Abstract: Purpose: This study was performed to investigate the effects of common polymorphisms in CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of bisoprolol in hypertensive Chinese patients. Methods: One hundred patients with essential… read more here.
Keywords: cyp2d6; weeks treatment; cyp2d6 cyp3a5; cyp3a5 polymorphisms ... See more keywords