Effects of diltiazem, a moderate inhibitor of CYP3A4, on the pharmacokinetics of tamsulosin in different CYP2D6 genotypes
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DOI: 10.1007/s12272-018-1030-6
Abstract: Tamsulosin, a selective antagonist of the α1-adrenoceptor, is primarily metabolized by CYP3A4 and CYP2D6, and tamsulosin exposure is significantly increased according to the genetic polymorphism of CYP2D6. In this study, we investigated the effects of… read more here.
Keywords: different cyp2d6; tamsulosin; cyp2d6 genotypes; cyp3a4 ... See more keywords