Simultaneous quantification of the CYP2D6 substrate yohimbine, its metabolite 11-OH-yohimbine, and the CYP2D6 inhibitor paroxetine in human plasma
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DOI: 10.1039/c9ay01715a
Abstract: We developed and validated a human plasma LC-MS/MS assay according to FDA guidelines to determine the impact of the CYP2D6 inhibitor paroxetine on the pharmacokinetics of the assumed specific CYP2D6 substrate yohimbine. read more here.
Keywords: inhibitor paroxetine; cyp2d6 inhibitor; human plasma; cyp2d6 substrate ... See more keywords