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Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.00027

Abstract: Previously, we showed vascular endothelial overexpression of human-CYP2J2 enhances coronary reactive hyperemia in Tie2-CYP2J2 Tr mice, and eNOS−/− mice had overexpression of CYP2J-epoxygenase with adenosine A2A receptor-induced enhance relaxation, but we did not see the… read more here.

Keywords: relaxation; response; cyp2j5; mice ... See more keywords