Oxidative metabolism of koumine is mainly catalyzed by microsomal CYP3A4/3A5
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DOI: 10.1080/00498254.2016.1213925
Abstract: Abstract 1. Gelsemium elegans Benth (Loganiaceae) is a toxic plant that can be used for committing suicide besides alleviating pains. Its anti-inflammatory and analgesic effect mainly come from its active ingredient, namely koumine. Koumine, an indole… read more here.
Keywords: oxidative metabolism; koumine; metabolism koumine; cyp3a4 3a5 ... See more keywords