Involvement of cytochrome P450 in cisplatin treatment: implications for toxicity
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3358-x
Abstract: PurposeThe aim of this study is to evaluate the relationship between the CYP450 enzyme family and cisplatin toxicity.MethodsThis article examined a collection of studies suggesting that CYP450 enzymes may influence cisplatin toxicity. We performed a… read more here.
Keywords: involvement cytochrome; cisplatin; toxicity; cisplatin toxicity ... See more keywords
Evaluation of potential herb-drug interactions based on the effect of Suxiao Jiuxin Pill on CYP450 enzymes and transporters.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114408
Abstract: ETHNOPHARMACOLOGY RELEVANCE Suxiao jiuxin pill (SJP) is a Chinese medical drug with anti-inflammatory, anti-apoptotic, and vasodilatory function. It is widely used in combination with other drugs for the treatment of coronary heart disease (CHD) and… read more here.
Keywords: effect; drug; sjp; enzymes transporters ... See more keywords
Widespread basal cytochrome P450 expression in extrahepatic bovine tissues and isolated cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dairy science"
DOI: 10.3168/jds.2019-17071
Abstract: Periparturient cattle face increased risk of both metabolic and infectious diseases. Factors contributing to this predisposition include oxidized polyunsaturated fatty acids, also known as oxylipids, whose production is altered during the periparturient period and in… read more here.
Keywords: cytochrome p450; expression; cyp450 enzymes; bovine tissues ... See more keywords
Arachidonic Acid Metabolites of CYP450 Enzymes and HIF-1α Modulate Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats under Acute and Intermittent Hyperbaric Oxygenation
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21176353
Abstract: Acetylcholine-induced vasorelaxation (AChIR) and responses to reduced pO2 (hypoxia-induced relaxation (HIR), 0% O2) were assessed in vitro in aortic rings of healthy male Sprague-Dawley rats (N = 252) under hyperbaric (HBO2) protocols. The studied groups… read more here.
Keywords: hbo2; 24h hbo2; group; hbo2 group ... See more keywords