Monitoring of autoantibodies against CYP4Z1 in patients with colon, ovarian, or prostate cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Immunobiology"
DOI: 10.1016/j.imbio.2021.152174
Abstract: We have previously monitored the detection of autoantibodies (aAbs) directed against CYP4Z1 in the sera of breast and lung cancer patients. In the present study, the occurence of anti-CYP4Z1 aAbs in patients suffering from colon… read more here.
Keywords: cancer; cyp4z1; ovarian prostate; prostate cancer ... See more keywords
Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c00101
Abstract: Mammary tissue-restricted cytochrome P450 4Z1 (CYP4Z1) has garnered interest for its potential role in breast cancer progression. CYP4Z1-dependent metabolism of arachidonic acid preferentially generates 14,15-epoxyeicosatrienoic acid (14,15-EET), a metabolite known to influence cellular proliferation, migration,… read more here.
Keywords: cyp4z1; p450 4z1; cytochrome p450; mechanism based ... See more keywords