The natural occurring Y129F polymorphism in Rhizopus oryzae (R. arrhizus) Cyp51Ap accounts for its intrinsic Voriconazole Resistance.
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DOI: 10.1093/mmy/myab052
Abstract: Rhizopus oryzae (heterotypic synonym: R. arrhizus) intrinsic voriconazole and fluconazole resistance has been linked to its CYP51A gene. However, the amino acid residues involved in this phenotype have not yet been established. A comparison between… read more here.
Keywords: intrinsic voriconazole; cyp51ap; rhizopus oryzae; resistance ... See more keywords