A Missense Variant Arg611Cys in LIPE which Encodes Hormone Sensitive Lipase Decreases Lipolysis and Increases Risk of Type 2 Diabetes in American Indians.
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DOI: 10.1002/dmrr.3504
Abstract: AIMS Hormone sensitive lipase (HSL), encoded by the LIPE gene, is involved in lipolysis. Based on prior animal and human studies, LIPE was analyzed as a candidate gene for the development of type 2 diabetes… read more here.
Keywords: cys allele; american indians; hormone sensitive; lipolysis ... See more keywords