The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10.
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DOI: 10.1080/15548627.2022.2126617
Abstract: In the N-degron pathway, N-recognins recognize cognate substrates for degradation via the ubiquitin (Ub)-proteasome system (UPS) or the autophagy-lysosome system (hereafter autophagy). We have recently shown that the autophagy receptor SQSTM1/p62 (sequestosome 1) is an… read more here.
Keywords: cys degron; degron; sqstm1 p62; degron pathway ... See more keywords