Evaluation of the radioprotective ability of cystamine for 150 keV – 500 MeV proton irradiation: a Monte Carlo track chemistry simulation study
Sign Up to like & getrecommendations! Published in 2019 at "Canadian Journal of Chemistry"
DOI: 10.1139/cjc-2018-0382
Abstract: Cystamine, an organic diamino-disulfide, is among the best of the known radiation-protective compounds, although the underlying molecular mechanisms by which it operates remain poorly understood. This study aims to use the aqueous ferrous sulfate (Fricke)… read more here.
Keywords: cystamine; kev 500; monte carlo; 150 kev ... See more keywords
Cystamine slows but not inverses the progression of monocrotaline-induced pulmonary arterial hypertension in rats.
Sign Up to like & getrecommendations! Published in 2018 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2017-0720
Abstract: Tissue transglutaminase (TG2) plays an important role in pulmonary arterial hypertension (PAH). Previous research indicate that TG2 and protein serotonylation catalyzed by TG2 are upregulated in PAH. Serotonin transporter inhibitor fluoxetine ameliorates PAH via inhibition… read more here.
Keywords: monocrotaline; tg2; pulmonary arterial; monocrotaline induced ... See more keywords
Cysteamine/Cystamine Exert Anti-Mycobacterium abscessus Activity Alone or in Combination with Amikacin
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021203
Abstract: Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria. In this study, we aim to test the potential activity of the FDA- and… read more here.
Keywords: cysteamine cystamine; activity; cystamine; mycobacterium abscessus ... See more keywords