Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14295
Abstract: Crohn’s disease (CD) is characterized by the chronic inflammation of the gastrointestinal tract. A dysbiotic microbiome and a defective immune system are linked to CD, where hydrogen sulfide (H2S) microbial producers positively correlate with the… read more here.
Keywords: structural analysis; atopobium parvulum; crohn disease; cysteine ... See more keywords
Mammalian D‐cysteine: A novel regulator of neural progenitor cell proliferation
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200002
Abstract: D‐amino acids are being recognized as functionally important molecules in mammals. We recently identified endogenous D‐cysteine in mammalian brain. D‐cysteine is present in neonatal brain in substantial amounts (mM) and decreases with postnatal development. D‐cysteine… read more here.
Keywords: cell; proliferation; neural progenitor; regulator ... See more keywords
Proteome‐Wide Survey of Cysteine Oxidation by Using a Norbornene Probe
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900729
Abstract: Rapid detection of cysteine oxidation in living cells is critical in advancing our understanding of responses to reactive oxygen species (ROS) and oxidative stress. Accordingly, there is a need to develop chemical probes that facilitate… read more here.
Keywords: oxidation; cysteine; norbornene probe; cysteine oxidation ... See more keywords
Mammalian D-Cysteine: A new addition to the growing family of biologically relevant D-amino acids.
Sign Up to like & getrecommendations! Published in 2023 at "Chirality"
DOI: 10.1002/chir.23555
Abstract: Mammalian D-Cysteine is racemized from L-cysteine by serine racemase, a pyridoxal phosphate (PLP)-dependent enzyme. Endogenous D-Cysteine plays a role in neural development by inhibiting proliferation of neural progenitor cells (NPCs) via protein kinase B (AKT)… read more here.
Keywords: cysteine new; family; mammalian cysteine; new addition ... See more keywords
Operationally Convenient and Scalable Asymmetric Synthesis of (2S)‐ and (2R)‐α‐(Methyl)cysteine Derivatives through Alkylation of Chiral Alanine Schiff Base NiII Complexes
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700018
Abstract: This research demonstrates that the methylation of N-benzyl cysteine Schiff bases derived Ni(II) complexes leads to the formation of the corresponding dehydroalanine containing products and cannot be used for preparation of the target -(methyl)cysteine. In… read more here.
Keywords: alanine schiff; cysteine; methyl cysteine; convenient scalable ... See more keywords
Biochemical characterization of argininosuccinate lyase from M. tuberculosis: significance of a c‐terminal cysteine in catalysis and thermal stability
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1683
Abstract: Arginine biosynthesis pathway is crucial to the survival and pathogenesis of Mycobacterium tuberculosis (Mtb). Arginine is a critical amino acid that contributes to the inflection of cellular immune responses during pathogenesis. Argininosuccinate lyase from Mtb… read more here.
Keywords: cysteine; cys441; tuberculosis; activity ... See more keywords
Novel Anti-Biofouling Soft Contact Lens: l-Cysteine Conjugated Amphiphilic Conetworks via RAFT and Thiol-Ene Click Chemistry.
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201600444
Abstract: A unique l-cysteine conjugated antifouling amphiphilic conetwork (APCN) is synthesized through end-crosslinking of well-defined triblock copolymers poly(allyl methacrylate)-b-poly(ethylene glycol)-b-poly(allyl methacrylate) via a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene "click" chemistry. The… read more here.
Keywords: click chemistry; raft; cysteine; chemistry ... See more keywords
Fluorescent Imaging for Cysteine Detection In Vivo with High Selectivity
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DOI: 10.1002/open.201900045
Abstract: Abstract As an essential amino acid, cysteine is involved in various biosynthetic and metabolic processes, such as protein synthesis, hormone synthesis, and redox homeostatic maintenance. Inordinate cysteine levels are often associated with serious diseases. Thus,… read more here.
Keywords: detection vivo; fluorescent imaging; cysteine detection; cysteine ... See more keywords
A Carbon Paste Electrode Modified by Bentonite and l‐Cysteine for Simultaneous Determination of Ascorbic and Uric Acids: Application in Biological Fluids
Sign Up to like & getrecommendations! Published in 2023 at "ChemistryOpen"
DOI: 10.1002/open.202200201
Abstract: Abstract A novel modification of a paste carbon electrode by Bentonite (Bent) and l‐Cysteine (l‐Cyst) was carried out for uric acid (UA) and ascorbic acid (AA) detection and quantification. Morphological and compositional characterization of the… read more here.
Keywords: electrode; carbon paste; paste electrode; paste ... See more keywords
Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis
Sign Up to like & getrecommendations! Published in 2017 at "Protein Science"
DOI: 10.1002/pro.3141
Abstract: Nucleoside hydrolases (NHs) catalyze the hydrolysis of the N‐glycoside bond in ribonucleosides and are found in all three domains of life. Although in parasitic protozoa a role in purine salvage has been well established, their… read more here.
Keywords: cysteine; nucleoside hydrolase; group; active site ... See more keywords
Structure–function analysis of cysteine residues in the plasmodium falciparum chitinase, PfCHT1
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4289
Abstract: The Plasmodium ookinete uses chitinase activity to penetrate the acellular, chitin‐containing peritrophic matrix to invade the mosquito vector. Plasmodium ookinetes from different parasite clades secrete two structurally distinct forms of chitinase, one, a short form… read more here.
Keywords: chitinase; chitin; plasmodium; pfcht1 ... See more keywords