Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.07.003
Abstract: The objective of this study was to determine the effect of ligustrazine (TMP) on cadmium (Cd)-induced nephrotoxicity and its relevant mechanism. TMP (50mg/kg) was injected intraperitoneally (i.p.) into rats 1h prior to CdCl2 exposure (at… read more here.
Keywords: biosynthesis; rats exposed; cadmium; ligustrazine ... See more keywords
Mycobacterium tuberculosis cysteine biosynthesis genes mec+-cysO-cysM confer resistance to clofazimine.
Sign Up to like & getrecommendations! Published in 2019 at "Tuberculosis"
DOI: 10.1016/j.tube.2019.02.002
Abstract: The Mycobacterium tuberculosis mec+-cysO-cysM gene cluster was shown to be part of a novel cysteine biosynthesis pathway in vitro, but little is known about its essentiality or role in M. tuberculosis physiology. In this study,… read more here.
Keywords: tuberculosis; cysteine biosynthesis; mec cyso; cyso cysm ... See more keywords
Cystathionine β-synthase is involved in cysteine biosynthesis and H2S generation in Toxoplasma gondii
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71469-x
Abstract: Cystathionine β-synthase (CBS) catalyzes the condensation of serine and homocysteine to water and cystathionine, which is then hydrolyzed to cysteine, α-ketobutyrate and ammonia by cystathionine γ-lyase (CGL) in the reverse transsulfuration pathway. The protozoan parasite… read more here.
Keywords: cystathionine synthase; gondii; cystathionine; toxoplasma gondii ... See more keywords
The coral Acropora loripes genome reveals an alternative pathway for cysteine biosynthesis in animals
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq0304
Abstract: The metabolic capabilities of animals have been derived from well-studied model organisms and are generally considered to be well understood. In animals, cysteine is an important amino acid thought to be exclusively synthesized through the… read more here.
Keywords: pathway cysteine; cysteine biosynthesis; biosynthesis animals; alternative pathway ... See more keywords