Human 8‐Oxoguanine Glycosylase OGG1 Cleaves Abasic Sites and Covalently Conjugates to 3′‐DNA Termini via Cysteine and Histidine Addition
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DOI: 10.1002/cbic.202400705
Abstract: 8‐Oxoguanine glycosylase 1 (OGG1) repairs the major oxidative DNA damage, 8‐oxo‐2′‐deoxyguanosine. It has been reported that OGG1 incises the most frequently formed DNA lesion, apurinic/apyrimidinic (AP) site, and in the process a stable DNA‐OGG1 cross‐link… read more here.
Keywords: dna termini; cysteine histidine; histidine addition; glycosylase ogg1 ... See more keywords