Proteome‐Wide Survey of Cysteine Oxidation by Using a Norbornene Probe
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900729
Abstract: Rapid detection of cysteine oxidation in living cells is critical in advancing our understanding of responses to reactive oxygen species (ROS) and oxidative stress. Accordingly, there is a need to develop chemical probes that facilitate… read more here.
Keywords: oxidation; cysteine; norbornene probe; cysteine oxidation ... See more keywords
The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2017.01.008
Abstract: The reversible oxidation of protein cysteine residues is well recognized as an important regulatory mechanism in redox-dependent cell signaling. Cysteine oxidation is diverse in nature and involves various post-translational modifications (sulfenic acids, disulfides, etc.) and… read more here.
Keywords: oxidation; cys soh; redox; cysteine oxidation ... See more keywords
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
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DOI: 10.1038/s41467-020-19372-x
Abstract: Understanding the conformational sampling of translation-arrested ribosome nascent chain complexes is key to understand co-translational folding. Up to now, coupling of cysteine oxidation, disulfide bond formation and structure formation in nascent chains has remained elusive.… read more here.
Keywords: oxidation disulfide; exit tunnel; cysteine oxidation; formation ... See more keywords
Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells.
Sign Up to like & getrecommendations! Published in 2023 at "Cell chemical biology"
DOI: 10.2139/ssrn.4144958
Abstract: Reactive oxygen species (ROS) can modulate protein function through cysteine oxidation. Identifying protein targets of ROS can provide insight into uncharacterized ROS-regulated pathways. Several redox-proteomic workflows, such as oxidative isotope-coded affinity tags (OxICAT), exist to… read more here.
Keywords: cysteine oxidation; oxidation; localized cysteine; oxidation events ... See more keywords
Identifying Redox-Sensitive Cysteine Residues in Mitochondria
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DOI: 10.3390/antiox12050992
Abstract: The mitochondrion is the primary energy generator of a cell and is a central player in cellular redox regulation. Mitochondrial reactive oxygen species (mtROS) are the natural byproducts of cellular respiration that are critical for… read more here.
Keywords: cysteine oxidation; redox sensitive; oxidation; redox ... See more keywords