Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling.
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DOI: 10.1021/acs.molpharmaceut.7b00832
Abstract: Cysteine residues on proteins serve a variety of catalytic and regulatory functions due to the high nucleophilicity and redox activity of the thiol group. Quantitative proteomic platforms for profiling cysteine reactivity can provide valuable information… read more here.
Keywords: reactivity profiling; cysteine; iodoacetamide alkyne; isotopically labeled ... See more keywords