Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-018-9751-z
Abstract: Uveal melanoma is a rare, but deadly, form of eye cancer that arises from melanocytes within the uveal tract. Although advances have emerged in treatment of the primary tumour, patients are still faced with vision… read more here.
Keywords: melanoma; cysteinyl leukotriene; leukotriene receptor; uveal melanoma ... See more keywords
Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
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DOI: 10.1038/s41597-020-00729-2
Abstract: Structural studies of challenging targets such as G protein-coupled receptors (GPCRs) have accelerated during the last several years due to the development of new approaches, including small-wedge and serial crystallography. Here, we describe the deposition… read more here.
Keywords: cysteinyl leukotriene; wedge; small wedge; wedge synchrotron ... See more keywords
Possible Therapeutic Potential of Cysteinyl Leukotriene Receptor Antagonist Montelukast in Treatment of SARS-CoV-2-Induced COVID-19
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DOI: 10.1159/000518359
Abstract: Background: The coronavirus disease-19 (COVID-19) pandemic is a serious devastating disease and has posed a global health emergency. So far, there is not any specific therapy approved till date to control the clinical symptoms of… read more here.
Keywords: cysteinyl leukotriene; control; covid; possible therapeutic ... See more keywords
Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer
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DOI: 10.18632/oncotarget.16718
Abstract: Cysteinyl leukotriene receptor 1 (CysLT1R) has been shown to be up-regulated in the adenocarcinomas of colorectal cancer patients, which is associated with a poor prognosis. In a spontaneous model of colon cancer, CysLT1R disruption was… read more here.
Keywords: cysteinyl leukotriene; leukotriene receptor; colon; model ... See more keywords