Articles with "cystine dense" as a keyword



Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager

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Published in 2022 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.abn0402

Abstract: Cystine-dense peptides (CDPs) are a miniprotein class that can drug difficult targets with high affinity and low immunogenicity. Tools for their design, however, are not as developed as those for small-molecule and antibody drugs. CDPs… read more here.

Keywords: cell engager; cdp; dense; cystine dense ... See more keywords