Crystal structure of Arabidopsis thaliana cytidine deaminase.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.084
Abstract: Cytidine deaminase (CDA) catalyzes the (deoxy)cytidine deamination to (deoxy)uridine, which involves in the catabolic and salvage pathways of pyrimidine nucleotides in plants. CDA serves as a prototype of the cytidine deaminase superfamily that contains a… read more here.
Keywords: crystal structure; structure arabidopsis; arabidopsis thaliana; cytidine ... See more keywords
Cytidine Diphosphoramidate Kinase: An Enzyme Required for the Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00279
Abstract: Campylobacter jejuni, a leading cause of gastroenteritis, produces a capsular polysaccharide that is derivatized with a unique O-methyl phosphoramidate (MeOPN) modification. This modification contributes to serum resistance and invasion of epithelial cells. Previously, the first… read more here.
Keywords: campylobacter jejuni; diphosphoramidate; kinase; cytidine diphosphoramidate ... See more keywords
Modeling pK Shift in DNA Triplexes Containing Locked Nucleic Acids
Sign Up to like & getrecommendations! Published in 2018 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.7b00741
Abstract: The protonation states for nucleic acid bases are difficult to assess experimentally. In the context of DNA triplex, the protonation state of cytidine in the third strand is particularly important, because it needs to be… read more here.
Keywords: dna; dna triplex; cytidine; third strand ... See more keywords
Characterization of uridine-cytidine kinase like-1 nucleoside kinase activity and its role in tumor growth
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DOI: 10.1042/bcj20210770
Abstract: Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine… read more here.
Keywords: cytidine; uridine cytidine; tumor growth; kinase ... See more keywords
Self-organization of parS centromeres by the ParB CTP hydrolase
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DOI: 10.1126/science.aay3965
Abstract: CTP hydrolysis organizes chromosomes The bacterial DNA parS centromere recruits the ParB protein to the bacterial chromosome. Soh et al. found that the widespread family of ParB proteins not only bind DNA but also bind… read more here.
Keywords: parb protein; parb ctp; ctp; cytidine ... See more keywords
The cytidine deaminase APOBEC3G contributes to cancer mutagenesis and clonal evolution in bladder cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-2912
Abstract: Mutagenic processes leave distinct signatures in cancer genomes. The mutational signatures attributed to APOBEC3 cytidine deaminases are pervasive in human cancers. However, data linking individual APOBEC3 proteins to cancer mutagenesis in vivo are limited. Here,… read more here.
Keywords: cytidine; cancer mutagenesis; apobec3g; bladder cancer ... See more keywords
Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice
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DOI: 10.3390/nu15051147
Abstract: Cytidine and uridine are endogenous metabolites in the pyrimidine metabolism pathway, and cytidine is a substrate that can be metabolized into uridine via cytidine deaminase. Uridine has been widely reported to be effective in regulating… read more here.
Keywords: metabolism; gut microbiota; cytidine; composition mice ... See more keywords