A Chemical Signature for Cytidine Acetylation in RNA.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b06636
Abstract: N4-acetylcytidine (ac4C) is a highly conserved modified RNA nucleobase whose formation is catalyzed by the disease-associated N-acetyltransferase 10 (NAT10). Here we report a sensitive chemical method to localize ac4C in RNA. Specifically, we characterize the… read more here.
Keywords: acetylation; cytidine acetylation; signature cytidine; acetylation rna ... See more keywords
Quantitative nucleotide resolution profiling of RNA cytidine acetylation by ac4C-seq.
Sign Up to like & getrecommendations! Published in 2021 at "Nature protocols"
DOI: 10.1038/s41596-021-00501-9
Abstract: A prerequisite to defining the transcriptome-wide functions of RNA modifications is the ability to accurately determine their location. Here, we present N4-acetylcytidine (ac4C) sequencing (ac4C-seq), a protocol for the quantitative single-nucleotide resolution mapping of cytidine… read more here.
Keywords: ac4c seq; cytidine acetylation; nucleotide resolution;