Potential SARS-CoV-2 RdRp inhibitors of cytidine derivatives: Molecular docking, molecular dynamic simulations, ADMET, and POM analyses for the identification of pharmacophore sites
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DOI: 10.1371/journal.pone.0273256
Abstract: The RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 is one of the optimum targets for antiviral drug design and development. The hydroxyl groups of cytidine structures were modified with different aliphatic and aromatic groups to obtain… read more here.
Keywords: molecular docking; cytidine derivatives; pharmacophore; docking molecular ... See more keywords