Articles with "cytoarchitecture despite" as a keyword



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Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-62047-2

Abstract: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) is a photoreceptor-specific chaperone that stabilizes the effector enzyme of phototransduction, cGMP phosphodiesterase 6 (PDE6). Mutations in the AIPL1 gene cause a severe inherited retinal dystrophy, Leber congenital amaurosis… read more here.

Keywords: reduced levels; cytoarchitecture despite; mutant aipl1; retinal organoids ... See more keywords