Regulation of Neisseria meningitidis cytochrome bc 1 components by NrrF, a Fur‐controlled small noncoding RNA
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DOI: 10.1002/2211-5463.12266
Abstract: NrrF is a small regulatory RNA of the human pathogen Neisseria meningitidis. NrrF was previously shown to repress succinate dehydrogenase (sdhCDAB) under control of the ferric uptake regulator (Fur). Here, we provide evidence that cytochrome… read more here.
Keywords: cytochrome components; rna; cytochrome bc1; meningitidis cytochrome ... See more keywords
Interaction of picolinamide fungicide primary metabolites UK-2A and CAS-649 with the cytochrome bc1 complex Qi site: mutation effects and modeling in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.6893
Abstract: BACKGROUND Fenpicoxamid and florylpicoxamid are picolinamide fungicides targeting the Qi site of the cytochrome bc1 complex, via their primary metabolites UK-2A and CAS-649, respectively. We explore binding interactions and resistance mechanisms for picolinamides, antimycin A… read more here.
Keywords: interaction; cas 649; g37; resistance ... See more keywords
Cytochrome bc1 Complex: Potential Breach to Improve the Activity of Phenazines on Xanthomonas.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c03317
Abstract: The effects of the natural pesticides, phenazines, were reported to be limited by some tolerant metabolism processes within Xanthomonas. Our previous studies suggested that the functional cytochrome bc1 complex, the indispensable component of the respiration… read more here.
Keywords: phenazines xanthomonas; bc1 complex; bc1; improve activity ... See more keywords
Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis
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DOI: 10.1038/s41598-019-44887-9
Abstract: The influence of carbon metabolism on oxidative phosphorylation is poorly understood in mycobacteria. M. tuberculosis expresses two respiratory terminal oxidases, the cytochrome bc1:aa3 and the cytochrome bd oxidase, which are jointly required for oxidative phosphorylation… read more here.
Keywords: cytochrome bc1; drugs targeting; carbon metabolism; bc1 aa3 ... See more keywords
Nitric Oxide-Dependent Electron Transport Chain Inhibition by the Cytochrome bc1 Inhibitor and Pretomanid Combination Kills Mycobacterium tuberculosis
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DOI: 10.1128/aac.00956-21
Abstract: Mycobacterium tuberculosis, the causative agent of human tuberculosis, harbors a branched electron transport chain, preventing the bactericidal action of cytochrome bc1 inhibitors (e.g., TB47). Here, we investigated, using luminescent mycobacterial strains, the in vitro combination… read more here.
Keywords: combination; cytochrome bc1; tuberculosis; bc1 inhibitors ... See more keywords
In silico investigation of cytochrome bc1 molecular inhibition mechanism against Trypanosoma cruzi
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010545
Abstract: Chagas’ disease is a neglected tropical disease caused by the kinetoplastid protozoan Trypanosoma cruzi. The only therapies are the nitroheterocyclic chemicals nifurtimox and benznidazole that cause various adverse effects. The need to create safe and… read more here.
Keywords: cruzi; action; mechanism; cytochrome ... See more keywords
Assembly of the Multi-Subunit Cytochrome bc1 Complex in the Yeast Saccharomyces cerevisiae
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DOI: 10.3390/ijms231810537
Abstract: The cytochrome bc1 complex is an essential component of the mitochondrial respiratory chain of the yeast Saccharomyces cerevisiae. It is composed of ten protein subunits, three of them playing an important role in electron transfer… read more here.
Keywords: bc1 complex; yeast saccharomyces; bc1; cytochrome bc1 ... See more keywords