Co-Crystal Structure-Guided Optimization of Dual-Functional Small Molecules for Improving the Peroxygenase Activity of Cytochrome P450BM3
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DOI: 10.3390/ijms23147901
Abstract: We recently developed an artificial P450–H2O2 system assisted by dual-functional small molecules (DFSMs) to modify the P450BM3 monooxygenase into its peroxygenase mode, which could be widely used for the oxidation of non-native substrates. Aiming to… read more here.
Keywords: cytochrome p450bm3; small molecules; peroxygenase; crystal structure ... See more keywords