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   Articles with "cytogenetic abnormalities" as a keyword



Cytogenetic abnormalities in systemic mastocytosis: WHO subcategory‐specific incidence and prognostic impact among 348 informative cases

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recommendations! Published in 2018 at "American Journal of Hematology"

DOI: 10.1002/ajh.25265

Abstract: The World Health Organization (WHO) system lists five morphological categories of systemic mastocytosis (SM): indolent (ISM), smoldering, SM with an associated hematological neoplasm (SM‐AHN), aggressive (ASM) and mast cell leukemia (MCL). Recent studies have highlighted… read more here.

Keywords: incidence; cytogenetic abnormalities; systemic mastocytosis; abnormal karyotype ... See more keywords
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Age and cytogenetic abnormalities☆

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recommendations! Published in 2018 at "Hematology, Transfusion and Cell Therapy"

DOI: 10.1016/j.htct.2018.01.004

Abstract: its relationship to cancer. Nat Genet. 2012;44(6):642–50. 5. Sahin E, Depinho RA. Linking functional decline of telomeres, n this issue, the Hematology, Transfusion and Cell Therapy ournal is publishing a paper of Alves et al.… read more here.

Keywords: cytogenetic abnormalities; hematology; onco hematological; age cytogenetic ... See more keywords

Prognostic impact of cytogenetic abnormalities in adult patients with Philadelphia chromosome-negative ALL who underwent an allogeneic transplant

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recommendations! Published in 2019 at "Bone Marrow Transplantation"

DOI: 10.1038/s41409-019-0585-2

Abstract: Although cytogenetic abnormalities at diagnosis are recognized as an important prognostic factor in patients with Philadelphia chromosome (Ph)-negative acute lymphoblastic leukemia (ALL), the prognostic impact has not been evaluated in allogeneic stem cell transplant (allo-SCT)… read more here.

Keywords: cytogenetic abnormalities; group; patients philadelphia; philadelphia chromosome ... See more keywords

Landscapes of immunoglobulin heavy-chain gene repertoire and its cytogenetic abnormalities in Chinese patients with multiple myeloma

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-04158-2

Abstract: Multiple myeloma (MM) is a heterogeneous disease, the full understanding of whose pathogenesis remains elusive. While B-cell receptors are known to play a pivotal role in myeloma pathogenesis, the characterization of immunoglobulin heavy-chain (IGH) gene… read more here.

Keywords: multiple myeloma; chinese patients; cytogenetic abnormalities; immunoglobulin heavy ... See more keywords

Cytogenetic abnormalities in patients with newly diagnosed multiple myeloma as a secondary primary malignancy: a retrospective study

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recommendations! Published in 2020 at "Hematology"

DOI: 10.1080/16078454.2020.1757330

Abstract: ABSTRACT Objectives: Multiple myeloma (MM) often develops as a secondary primary malignancy (SPM). The retinoblastoma susceptibility gene (RB1) was the first tumour suppressor gene to be identified. We pooled and analyzed available data to compare… read more here.

Keywords: cytogenetic abnormalities; secondary primary; abnormalities patients; multiple myeloma ... See more keywords

AML with inv(16)/t(16;16) and high-risk cytogenetic abnormalities: atypical features and unfavorable outcome

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recommendations! Published in 2022 at "Hematology"

DOI: 10.1080/16078454.2022.2078027

Abstract: ABSTRACT Objectives Acute myeloid leukemia (AML) with inv(16)/t(16;16) is among the most frequent AML subtypes. It is recognized by the detection of the CBFB-MYH11 fusion which confers a favorable prognosis, irrespective of the presence of… read more here.

Keywords: cytogenetic abnormalities; risk; high risk; aml inv ... See more keywords

Clinical and Cytogenetic Characteristics of Children With Leukemia 20-Year Retrospective Study

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recommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"

DOI: 10.1097/mph.0000000000002529

Abstract: Acute leukemias are the most common malignant diseases in childhood. The aims of this retrospective cohort study were to investigate the frequency of cytogenetic abnormalities in acute pediatric leukemia; the correlation between cytogenetic abnormalities and… read more here.

Keywords: year survival; year; leukemia; cytogenetic abnormalities ... See more keywords

Long‐term outcomes of aplastic anemia with cytogenetic abnormalities at diagnosis

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recommendations! Published in 2022 at "European Journal of Haematology"

DOI: 10.1111/ejh.13913

Abstract: To elucidate the clinical characteristics of AA patients with cytogenetic abnormalities. read more here.

Keywords: long term; anemia cytogenetic; term outcomes; cytogenetic abnormalities ... See more keywords

IGH cytogenetic abnormalities can be detected in multiple myeloma by imaging flow cytometry

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recommendations! Published in 2022 at "Journal of Clinical Pathology"

DOI: 10.1136/jcp-2022-208230

Abstract: Aims Cytogenetic abnormalities involving the IGH gene are seen in up to 55% of patients with multiple myeloma. Current testing is performed manually by fluorescence in situ hybridisation (FISH) on purified plasma cells. We aimed… read more here.

Keywords: abnormalities detected; imaging flow; involving igh; cytogenetic abnormalities ... See more keywords

Cytogenetic Abnormalities in Polycythemia Vera: Phenotypic Correlates and Prognostic Relevance in 669 Informative Cases

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recommendations! Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-193120

Abstract: Background Abnormal karyotype is not infrequent in polycythemia vera (PV) and has been associated with shortened survival (BJH 2018;182:437). In the current study, we utilized a large institutional database, in order to describe the spectrum… read more here.

Keywords: cytogenetic abnormalities; karyotype; abnormal karyotype; year diagnosis ... See more keywords

Correlation of flow cytometry ogata score with cytogenetic abnormalities in myelodysplastic syndromes.

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recommendations! Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-7380

Abstract: Background and Aims: Flow cytometry (FCM) is a fast valuable tool for detecting dysplasia in the diagnosis of MDS, with Ogata score being a simple and widely used. While phenotypic abnormalities detected by FCM often… read more here.

Keywords: correlation flow; cytogenetic abnormalities; flow cytometry; ogata score ... See more keywords