Prognostic Score and Cytogenetic Risk Classification for Chronic Lymphocytic Leukemia Patients: Center for International Blood and Marrow Transplant Research Report
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DOI: 10.1158/1078-0432.ccr-18-3988
Abstract: Purpose: To develop a prognostic model and cytogenetic risk classification for previously treated patients with chronic lymphocytic leukemia (CLL) undergoing reduced intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (HCT). Experimental Design: We performed a retrospective… read more here.
Keywords: blood; risk classification; risk; cytogenetic risk ... See more keywords
Association between Immunoglobulin Isotypes and Cytogenetic Risk Groups in Multiple Myeloma
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DOI: 10.1182/blood-2018-99-118831
Abstract: Introduction: Cytogenetic abnormalities (CAs) in multiple myeloma (MM) have prognostic significance and predict the risk of clonal evolution, disease progression, and response to treatment. The Revised International Scoring System (R-ISS) was recently updated to incorporate… read more here.
Keywords: risk; group; risk groups; risk cas ... See more keywords
Efficacy and safety of daratumumab, lenalidomide, and dexamethasone (D-Rd) in relapsed or refractory multiple myeloma (RRMM): Updated subgroup analysis of POLLUX based on cytogenetic risk.
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DOI: 10.1200/jco.2019.37.15_suppl.8038
Abstract: 8038 Background: High-risk cytogenetic abnormalities confer poor outcomes in MM patients (pts). In POLLUX, D-Rd demonstrated significant clinical benefit, including prolonged progression-free survival (PFS) vs lenalidomide and dexamethasone (Rd), and tolerability in RRMM pts. We… read more here.
Keywords: high risk; rrmm; risk; cytogenetic risk ... See more keywords