Analyses of the complex formation of staphylococcal enterotoxin A and the human gp130 cytokine receptor.
Sign Up to like & getrecommendations! Published in 2022 at "FEBS letters"
DOI: 10.1002/1873-3468.14292
Abstract: Superantigens (SAgs) are bacterial enterotoxins produced by Staphylococcus aureus. Staphylococcal enterotoxin type A (SEA), a staphylococcal superantigen, has been shown to bind to the cytokine signaling receptor glycoprotein 130 (gp130). The structural details as well… read more here.
Keywords: staphylococcal enterotoxin; gp130; cytokine; human gp130 ... See more keywords
Reply to the Letter “COVID‐19‐Associated Encephalopathy and Cytokine‐Mediated Neuroinflammation”
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Neurology"
DOI: 10.1002/ana.25856
Abstract: Muccioli et al proposed an interesting comparison between the case of encephalitis related to severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) infection we described and immune effector cell-associated neurotoxicity syndrome (ICANS). Indeed, the clinical phenotype characterized… read more here.
Keywords: cytokine; reply letter; neuroinflammation; covid ... See more keywords
Serum cytokine profile and clinicopathological findings in oral lichen planus, oral lichenoid lesions and stomatitis
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DOI: 10.1002/cre2.91
Abstract: The objective of this study was to examine if clinical and histopathological variables in patients with oral lichen planus (OLP), oral lichenoid lesions (OLL), and generalized stomatitis display different cytokine profiles and if concomitant contact… read more here.
Keywords: lichenoid lesions; cytokine; oral lichenoid; oral lichen ... See more keywords
Gating Harmonization Guidelines for Intracellular Cytokine Staining Validated in Second International Multiconsortia Proficiency Panel Conducted by Cancer Immunotherapy Consortium (CIC/CRI)
Sign Up to like & getrecommendations! Published in 2020 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24244
Abstract: Results from the first gating proficiency panel of intracellular cytokine staining (ICS) highlighted the value of using a consensus gating approach to reduce the variability across laboratories in reported %CD8+ or %CD4+ cytokine‐positive cells. Based… read more here.
Keywords: panel; cytokine; harmonization guidelines; proficiency panel ... See more keywords
Exploring joint HPA-inflammatory stress response profiles in adolescent girls: Implications for developmental models of neuroendocrine dysregulation.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22247
Abstract: Prior research has struggled to differentiate cortisol stress response patterns reflective of well-regulated versus dysregulated hypothalamic-pituitary-adrenal (HPA) axis function among adolescents. Here, we show how exploring profiles of joint HPA-inflammatory stress responsivity, and linking those… read more here.
Keywords: stress; cytokine; cortisol response; response ... See more keywords
SOCS3 is a suppressor of γc cytokine signaling and constrains generation of murine Foxp3+ regulatory T cells
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.201948307
Abstract: SOCS3 is a cytosolic inhibitor of cytokine signaling that suppresses the activation of cytokine receptor‐associated JAK kinases. Mechanistically, SOCS3 is recruited to a site in the cytokine receptors known as the SOCS3‐interaction motif, and then… read more here.
Keywords: cytokine; socs3; foxp3 regulatory; cytokine signaling ... See more keywords
Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post‐coculture with activated neutrophils
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29713
Abstract: The interaction of mesenchymal stromal cells (MSCs) with paracrine signals and immunological cells, and their responses and regenerative commitment thereafter, is understudied. In the current investigation, we compared MSCs from the umbilical cord blood (UCB),… read more here.
Keywords: cytokine; activated neutrophils; commitment; mscs ... See more keywords
Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3covr0520-272r
Abstract: Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome‐coronavirus‐2 infection often results from alveolar injury that impedes airway capacity and multi‐organ failure—both of which are associated with the hyperproduction of cytokines,… read more here.
Keywords: cytokine; biology; leukocyte; covid ... See more keywords
WHO International Standards and Reference Preparations for Cytokines and Growth Factors
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DOI: 10.1002/jlb.3lt0419-120
Abstract: The ability to quantify the activity of cytokines is an essential part of experimental and clinical investigation and is largely dependent upon the availability of suitable cytokine standards and reference reagents. The International Cytokine and… read more here.
Keywords: cytokine; cytokines growth; growth factors; reference ... See more keywords
Th1 cytokine gene polymorphism and the corresponding plasma cytokine levels: A comparative study in HIV-1 positive and exposed uninfected infants.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical virology"
DOI: 10.1002/jmv.27408
Abstract: The pro-inflammatory (Th1) cytokines namely IL-2, IL-6, IL-12, IFN-γ, TNF-α are vital in the clearance of HIV infection. This prospective cohort study aimed to evaluate the polymorphisms of Th1 cytokine genes and their corresponding plasma… read more here.
Keywords: cytokine; cytokine levels; hiv positive; th1 cytokine ... See more keywords
Can Hypericum perforatum (SJW) prevent cytokine storm in COVID‐19 patients?
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6764
Abstract: Dear Editor, Pandemic coronavirus disease 2019 (COVID-19), caused by SARSCoV-2 virus, mainly affects adult or aging individuals with fever, dry cough, and dyspnea of variable severity. In approximately 20% of patients, a widespread alveolar-interstitial pneumonia… read more here.
Keywords: covid patients; hpf; sjw extract; cytokine ... See more keywords