The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling
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DOI: 10.7554/elife.55164
Abstract: The cytokine, GDF15, is produced in pathological states which cause cellular stress, including cancer. When over expressed, it causes dramatic weight reduction, suggesting a role in disease-related anorexia. Here, we demonstrate that the GDF15 receptor,… read more here.
Keywords: gdf15 signals; gdf15; cytokine gdf15; cholecystokinin neurons ... See more keywords