Changes in the TCR repertoire of T‐cell subsets during culture of cytokine‐induced killer cells
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14501
Abstract: Cytokine‐induced killer (CIK) cells are a group of highly heterogeneous T cells expressing diverse T‐cell antigen receptors (TCRs), but possessing wide major histocompatibility complex (MHC)‐unrestricted antitumour activity, which have been used in the treatment of… read more here.
Keywords: cell subsets; induced killer; cell; cytokine induced ... See more keywords
Cytokine‐induced transient monocyte IL‐7Ra expression and the serum milieu in tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149661
Abstract: Bacterial components and cytokines induce IL‐7 receptor (IL‐7Rα) expression in monocytes. Aberrant low IL‐7Rα expression of monocytes has been identified as a feature of tuberculosis immunopathology. Here, we investigated the mechanisms underlying IL‐7Rα regulation of… read more here.
Keywords: tuberculosis; cytokine induced; induced transient; expression ... See more keywords
A novel Gymnema sylvestre extract protects pancreatic beta‐cells from cytokine‐induced apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6512
Abstract: Inflammatory cytokines such as interleukin‐1β, TNF‐α, and interferon‐γ are known to be involved in mediating β‐cells death in diabetes mellitus (DM). Thus, protecting from β‐cells death in patients with DM may be a useful target… read more here.
Keywords: gymnema sylvestre; induced apoptosis; cytokine induced; sylvestre extract ... See more keywords
Cytokine-Induced Acute Inflammatory Monoarticular Arthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7837-3_20
Abstract: Animal models of arthritis enable us to investigate the pathogenesis of the disease and also to evaluate new therapies. Here we describe two different acute inflammatory monoarticular arthritis models (mBSA/IL1β and mBSA/GM-CSF) providing a more… read more here.
Keywords: inflammatory monoarticular; monoarticular arthritis; acute inflammatory; cytokine induced ... See more keywords
Pharmacological stimulation of G-protein coupled receptor 40 alleviates cytokine-induced epithelial barrier disruption in airway epithelial Calu-3 cells.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.05.026
Abstract: Impairment of airway tight junctions induced by elevated levels of proinflammatory cytokines is implicated in the pathogenesis of inflammatory airway diseases. Pharmacological stimulation of G-protein coupled receptor (GPR) 40, a receptor of polyunsaturated fatty acids,… read more here.
Keywords: airway epithelial; pharmacological stimulation; disruption; cytokine induced ... See more keywords
Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-20947-1
Abstract: NK cells are innate lymphoid cells that can acquire a memory-like phenotype in vitro when stimulated with IL-12, IL-15, and IL-18. These cytokine-induced memory-like (CIML) NK cells exhibit prolonged lifespan and increased cytotoxicity, making them… read more here.
Keywords: cytokine induced; based cd16; cd16 expression; memory like ... See more keywords
The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption
Sign Up to like & getrecommendations! Published in 2020 at "Tissue Barriers"
DOI: 10.1080/21688370.2020.1832877
Abstract: ABSTRACT The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major actors of the intestinal barrier, which is impaired in inflammatory… read more here.
Keywords: oxo c12; microbiota; cytokine induced; quorum sensing ... See more keywords
Serum carcinoembryonic antigen levels as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with colorectal cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of immunology"
DOI: 10.1093/jimmun/vkaf037
Abstract: Cytokine-induced killer (CIK) cells, as an adoptive immunotherapy, are effective at treating colorectal cancer (CRC). However, whether an individual can benefit from CIK cell therapy remains unclear. In this study, we analyzed the long-term effects… read more here.
Keywords: cytokine induced; therapy; cell; induced killer ... See more keywords
Cytokine‐induced apoptosis inhibitor 1 (CIAPIN1) accelerates vascular remodelling via p53 and JAK2‐STAT3 regulation in vascular smooth muscle cells
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15631
Abstract: Abnormal vascular smooth muscle cell (VSMC) proliferation and migration lead to neointima formation, which eventually results in cardiovascular hyperplastic diseases. The molecular mechanisms underlying these cellular processes have not been fully understood. Cytokine‐induced apoptosis inhibitor… read more here.
Keywords: inhibitor ciapin1; apoptosis inhibitor; induced apoptosis; vascular smooth ... See more keywords
Cytokine Induced 3-D Organotypic Psoriasis Skin Model Demonstrates Distinct Roles for NF-κB and JAK Pathways in Disease Pathophysiology.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental dermatology"
DOI: 10.1111/exd.14551
Abstract: Psoriasis vulgaris is an inflammatory skin disease that affects 2-3% of the population worldwide. One of the major challenges in discovering novel therapies is the poor translatability of animal models to human disease. Therefore, it… read more here.
Keywords: cytokine production; psoriasis; cytokine induced; cytokine ... See more keywords
P09.01 Adoptive cell therapy of hematological malignancies using cytokine-induced killer cells retargeted with monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-itoc7.101
Abstract: Background Cytokine-Induced Killer (CIK) cells are a population of effector cells that represents a promising tool for adoptive cell therapy. They are easily expandable ex-vivo , safe, and exert cytotoxicity against a broad range of… read more here.
Keywords: none; cytokine induced; induced killer; cell ... See more keywords