Upregulation of hsa_circ_0004812 promotes COVID‐19 cytokine storm via hsa‐miR‐1287‐5p/IL6R, RIG‐I axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24666
Abstract: SARS‐CoV‐2 is one of the most contagious viruses in the Coronaviridae (CoV) family, which has become a pandemic. The aim of this study is to understand more about the role of hsa_circ_0004812 in the SARS‐CoV‐2… read more here.
Keywords: upregulation hsa; hsa; hsa circ; cytokine storm ... See more keywords
IL‐6 at the center of cytokine storm: Circulating inflammation mediators as biomarkers in hospitalized COVID‐19 patients
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24881
Abstract: The management of hospitalized COVID‐19 patients depends largely on controlling the intensified inflammatory response known as the cytokine storm. Candidate inflammatory cytokines can serve as new biomarkers for the management of hospitalized COVID‐19 patients. read more here.
Keywords: covid patients; hospitalized covid; storm circulating; cytokine storm ... See more keywords
Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3covr0520-272r
Abstract: Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome‐coronavirus‐2 infection often results from alveolar injury that impedes airway capacity and multi‐organ failure—both of which are associated with the hyperproduction of cytokines,… read more here.
Keywords: cytokine; biology; leukocyte; covid ... See more keywords
Can steroids reverse the severe COVID‐19 induced ‘cytokine storm’?
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DOI: 10.1002/jmv.26165
Abstract: Severe coronavirus disease (COVID‐19) is characterized by an excessive proinflammatory cytokine storm, resulting in acute lung injury and development of acute respiratory distress syndrome (ARDS). The role of corticosteroids is controversial in severe COVID‐19 pneumonia… read more here.
Keywords: steroids reverse; cytokine storm; covid; days median ... See more keywords
Can molecular mimicry explain the cytokine storm of SARS‐CoV‐2?: An in silico approach
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27040
Abstract: PARP14 and PARP9 play a key role in macrophage immune regulation. SARS‐CoV‐2 is an emerging viral disease that triggers hyper‐inflammation known as a cytokine storm. In this study, using in silico tools, we hypothesize about… read more here.
Keywords: sars cov; molecular mimicry; parp14 parp9; cytokine storm ... See more keywords
The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28751
Abstract: In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm, which is a hyperinflammatory medical condition caused by the excessive and uncontrolled… read more here.
Keywords: inflammatory cytokines; cytokine storm; storm; pro inflammatory ... See more keywords
[Fatal course of COVID-19 despite IL-6 receptor blockade in cytokine storm : Perimyocarditis and coagulopathy after administration of tocilizumab].
Sign Up to like & getrecommendations! Published in 2020 at "Der Anaesthesist"
DOI: 10.1007/s00101-020-00871-x
Abstract: A 59-year-old male patient was admitted to hospital diagnosed with moderate pneumonia associated with COVID-19. Upfront treatment with hydroxychloroquine and azithromycin was started. Due to a clinical deterioration (ARDS, circulatory shock) and greatly increased inflammation markers… read more here.
Keywords: treatment; cytokine storm; covid; tocilizumab ... See more keywords
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02725-2
Abstract: Cytokine storm can result from cancer immunotherapy or certain infections, including COVID-19. Though short-term immune-related adverse events are routinely described, longer-term immune consequences and sequential immune monitoring are not as well defined. In 2006, six… read more here.
Keywords: storm; clinical recovery; antibody; cytokine storm ... See more keywords
Cytokine storm and sepsis disease pathogenesis
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DOI: 10.1007/s00281-017-0639-8
Abstract: Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical syndrome related to the host response to infection. The severity of infections is due to an activation cascade that will lead… read more here.
Keywords: sepsis; cytokine; cytokine storm; cytokine production ... See more keywords
SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions
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DOI: 10.1007/s11010-020-03935-z
Abstract: The recent exposure of novel coronavirus strain, severe acute respiratory syndrome (SARS-CoV-2) has spread to different countries at an alarming rate. Faster transmission rate and genetic modifications have provoked scientists to search for an immediate… read more here.
Keywords: inflammatory responses; cytokine storm; responses host; cov mediated ... See more keywords
Pharmaco-Immunomodulatory Therapy in COVID-19
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DOI: 10.1007/s40265-020-01367-z
Abstract: The severe acute respiratory syndrome coronavirus 2 associated coronavirus disease 2019 (COVID-19) illness is a syndrome of viral replication in concert with a host inflammatory response. The cytokine storm and viral evasion of cellular immune… read more here.
Keywords: cytokine storm; covid; pharmaco immunomodulatory; immunomodulatory therapy ... See more keywords