Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.10.041
Abstract: BACKGROUND AND AIMS The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2) is highly expressed in small bowel (SB). Our aim was to identify factors influencing intestinal ACE2 expression in Crohn's disease (CD), ulcerative colitis… read more here.
Keywords: disease; ace2; cytokine therapy; ibd ... See more keywords
Anti-cytokine therapy and small molecule agents for the treatment of inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2021 at "European cytokine network"
DOI: 10.1684/ecn.2021.0472
Abstract: Inflammatory bowel disease (IBD), including Crohn disease and ulcerative colitis, with multifactorial etiologies has led to a global health-associated burden in many countries. Substantial efforts are devoted to understand the pathogenesis, behavioral and environmental triggers,… read more here.
Keywords: small molecule; cytokine therapy; treatment; disease ... See more keywords
Cytokine Therapy Combined with Nanomaterials Participates in Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122606
Abstract: Immunotherapy has gradually become an emerging treatment modality for tumors after surgery, radiotherapy, and chemotherapy. Cytokine therapy is a promising treatment for cancer immunotherapy. Currently, there are many preclinical theoretical bases to support this treatment… read more here.
Keywords: immunotherapy; therapy combined; cytokine therapy; cancer immunotherapy ... See more keywords