Highly sensitive detection of driver mutations from cytological samples and cfDNA in lung cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4330
Abstract: BACKGROUND Bronchoscopy is a minimally invasive procedure for establishing the diagnosis of lung cancer. It sometimes fails to obtain tissue samples but readily collects cytological samples. METHODS We developed PNA-LNA dual-PCR (PLDP), which amplified mutant… read more here.
Keywords: cytological samples; pldp; pcr; lung cancer ... See more keywords
Immunocytochemical Detection of ALK and ROS1 Rearrangements in Lung Cancer Cytological Samples.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1278-1_12
Abstract: The detection of molecular alterations such as ROS1 and ALK rearrangements is performed as part of the diagnosis of advanced-stage lung adenocarcinoma. These alterations allow the treatments with tyrosine kinase inhibitors. Cytological samples are very… read more here.
Keywords: detection; alk; cytological samples; alk ros1 ... See more keywords
Utilisation of cytological samples for multiplex immunofluorescence assay
Sign Up to like & getrecommendations! Published in 2021 at "Cytopathology"
DOI: 10.1111/cyt.12979
Abstract: Understanding the immune environment of non‐small cell lung cancer (NSCLC) is important for designing effective anticancer immunotherapies. We describe the use of multiplex immunofluorescence (mIF) assays to enable characterisation of the tumour‐infiltrating immune cells and… read more here.
Keywords: utilisation cytological; multiplex immunofluorescence; cytological samples; immunofluorescence ... See more keywords
Diagnostic performance of melanocytic markers for immunocytochemical evaluation of lymph-node melanoma metastases on cytological samples
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2020-206962
Abstract: Aims The diagnosis of metastatic cutaneous melanoma (CM) on lymph node fine needle aspiration samples may be challenging and usually requires confirmation by immunocytochemistry. However, the cytological material could be too scant to order a… read more here.
Keywords: melanocytic markers; cytological samples; performance; lymph node ... See more keywords
How to Diagnose Anaplastic Large Cell Lymphoma on Cytological Samples? A Series with Emphasis on Diagnostic Clue and Pitfalls.
Sign Up to like & getrecommendations! Published in 2023 at "Acta cytologica"
DOI: 10.1159/000528533
Abstract: INTRODUCTION Anaplastic large cell lymphoma (ALCL) is a rare mature T-cell non-Hodgkin's lymphoma characterized by large and pleomorphic neoplastic CD30-positive T cells. ALCL includes different subtypes with different clinical and biological features: systemic ALCL, primary… read more here.
Keywords: cell; diagnosis; cytological samples; alcl ... See more keywords
PRAME Immunocytochemistry for the Diagnosis of Melanoma Metastases in Cytological Samples
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12030646
Abstract: (1) Background: Fine-needle aspiration cytology is often used for the pre-operative diagnosis of melanoma metastases. The diagnosis may not be confidently established based on morphology alone, and immunocytochemistry is mandatory. The choice of the most… read more here.
Keywords: cytological samples; metastases cytological; diagnosis; diagnosis melanoma ... See more keywords
Comparison between Immunocytochemistry, FISH and NGS for ALK and ROS1 Rearrangement Detection in Cytological Samples
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810556
Abstract: The detection of ROS1 and ALK rearrangements is performed for advanced-stage non-small cell lung cancer. Several techniques can be used on cytological samples, such as immunocytochemistry (ICC), fluorescence in situ hybridization (FISH) and, more recently,… read more here.
Keywords: alk ros1; immunocytochemistry fish; fish ngs; cytological samples ... See more keywords