The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
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DOI: 10.1038/s41467-018-06607-1
Abstract: Clearance of invading microbes requires phagocytes of the innate immune system. However, successful pathogens have evolved sophisticated strategies to evade immune killing. The opportunistic human fungal pathogen Candida albicans is efficiently phagocytosed by macrophages, but… read more here.
Keywords: mononuclear phagocytes; peptide toxin; cytolysis; nlrp3 inflammasome ... See more keywords