Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells
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DOI: 10.1158/0008-5472.can-20-2569
Abstract: Tumor-repopulating cells evade CD8+ cytolytic T-cell killing through a mechanical softness mechanism, underlying the impediment of perforin pore formation at the immune synapse site. Biomechanics is a fundamental feature of a cell. However, the manner… read more here.
Keywords: tumor repopulating; softness; tumor; cell ... See more keywords