Cytoneme-mediated signaling essential for tumorigenesis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008415
Abstract: Communication between neoplastic cells and cells of their microenvironment is critical to cancer progression. To investigate the role of cytoneme-mediated signaling as a mechanism for distributing growth factor signaling proteins between tumor and tumor-associated cells,… read more here.
Keywords: tumor growth; mediated signaling; cytoneme mediated;
Cytoneme-mediated cell-cell contacts for Hedgehog reception
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.24045
Abstract: Morphogens regulate tissue patterning through their distribution in concentration gradients. Emerging research establishes a role for specialized signalling filopodia, or cytonemes, in morphogen dispersion and signalling. Previously we demonstrated that Hedgehog (Hh) morphogen is transported… read more here.
Keywords: reception; cell; mediated cell; cytoneme mediated ... See more keywords