Articles with "cytoplasmic aggregates" as a keyword



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Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons

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Published in 2022 at "Open Biology"

DOI: 10.1098/rsob.220187

Abstract: Splicing factor proline- and glutamine-rich (SFPQ) is a nuclear RNA-binding protein that is involved in a wide range of physiological processes including neuronal development and homeostasis. However, the mislocalization and cytoplasmic aggregation of SFPQ are… read more here.

Keywords: familial als; associated sfpq; sfpq cytoplasmic; sfpq ... See more keywords