Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies
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DOI: 10.1371/journal.pone.0272700
Abstract: Many members of the tripartite motif (TRIM) family of ubiquitin ligases localize in spherical, membrane-free structures collectively referred to as cytoplasmic bodies (CBs) in a concentration-dependent manner. These CBs may function as aggresome precursors or… read more here.
Keywords: cytoplasmic bodies; family ubiquitin; trim family; ubiquitin ligases ... See more keywords
Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagy
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DOI: 10.26508/lsa.202101160
Abstract: We describe a fully new remodeling event of the nuclear envelope surrounding the nucleolus: it partitions into its regular contact with the vacuole and a dramatic internalization of globular cytoplasmic portions within the nucleus. Membrane… read more here.
Keywords: boost autophagy; ingression cytoplasmic; cytoplasmic bodies; nuclear envelope ... See more keywords