Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.
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DOI: 10.1038/s41418-021-00917-6
Abstract: Cytoplasmic recognition of microbial lipopolysaccharides (LPS) in human cells is elicited by the caspase-4 and caspase-5 noncanonical inflammasomes, which induce a form of inflammatory cell death termed pyroptosis. Here we show that LPS-mediated activation of… read more here.
Keywords: caspase; cellular senescence; inflammasome; cytoplasmic innate ... See more keywords