Articles with "cytoplasmic tail" as a keyword



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The soluble cytoplasmic tail of CD45 (ct‐CD45) in human plasma contributes to keep T cells in a quiescent state

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Published in 2017 at "European Journal of Immunology"

DOI: 10.1002/eji.201646405

Abstract: The cytoplasmic tail of CD45 (ct‐CD45) is proteolytically cleaved and released upon activation of human phagocytes. It acts on T cells as an inhibitory, cytokine‐like factor in vitro. Here, we show that ct‐CD45 is abundant… read more here.

Keywords: plasma; cd45 cd45; human plasma; cytoplasmic tail ... See more keywords
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Glucose-induced internalization of the S. cerevisiae galactose permease Gal2 is dependent on phosphorylation and ubiquitination of its aminoterminal cytoplasmic tail.

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Published in 2021 at "FEMS yeast research"

DOI: 10.1093/femsyr/foab019

Abstract: The hexose permease Gal2 of Saccharomyces cerevisiae is expressed only in the presence of its physiological substrate galactose. Glucose tightly represses the GAL2 gene and also induces the clearance of the transporter from the plasma… read more here.

Keywords: cytoplasmic tail; tail; permease gal2; ubiquitination ... See more keywords
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A basic charge cluster near the C-terminus of the cytoplasmic tail contributes to the molecular stability of human herpesvirus 8 E3 ubiquitin ligases.

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Published in 2023 at "Microbiology and immunology"

DOI: 10.1111/1348-0421.13068

Abstract: Human herpesvirus 8 (HHV8; also known as Kaposi's sarcoma‐associated herpesvirus [KSHV]) utilizes the viral E3 ubiquitin ligase family members K3 and K5 for immune evasion. Both K3 and K5 mediate the ubiquitination of host MHC… read more here.

Keywords: cytoplasmic tail; tail; charge cluster; basic charge ... See more keywords
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Abstract 4911: Characterizing the role of podocalyxin's cytoplasmic tail domain in collective tumor invasion

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.am2020-4911

Abstract: High expression of the single-pass transmembrane sialomucin, podocalyxin, has been shown by many groups to correlate with poor disease outcome in a number of solid tumor types, including colorectal, ovarian, pancreatic and breast cancers. We… read more here.

Keywords: podocalyxin; invasion; collective tumor; cytoplasmic tail ... See more keywords
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Cytoplasmic Tail of MT1-MMP: A Hub of MT1-MMP Regulation and Function

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24065068

Abstract: MT1-MMP (MMP-14) is a multifunctional protease that regulates ECM degradation, activation of other proteases, and a variety of cellular processes, including migration and viability in physiological and pathological contexts. Both the localization and signal transduction… read more here.

Keywords: mt1 mmp; mmp; tail mt1; cytoplasmic tail ... See more keywords