Polyphenols of peanut (Arachis hypogaea L.) skin as bioprotectors of normal cells. Studies of cytotoxicity, cytoprotection and interaction with ROS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.103862
Abstract: Abstract Arachis hypogaea L. (peanut) skin is a potential source of natural antioxidants, and several studies have suggested the possibility of producing functional ingredients from this by-product of food industry. This investigation examined possible toxic… read more here.
Keywords: arachis hypogaea; hypogaea; cytoprotection; peanut arachis ... See more keywords
Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2017.08.003
Abstract: ABSTRACT Age‐related cataracts are closely associated with lens chronological aging, oxidation, calcium imbalance, hydration and crystallin modifications. Accumulating evidence indicates that misfolded proteins are generated in the endoplasmic reticulum (ER) by most cataractogenic stresses. To… read more here.
Keywords: age related; unfolded protein; cytoprotection; related cataracts ... See more keywords
General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11607-0
Abstract: General anesthetics are both neuroprotective and neurotoxic with unclear mechanisms. General anesthetics may control cell survival via their effects on autophagy by activation of type 1 inositol triphosphate receptor (InsP3R-1). DT40 or SH-SY5Y cells with… read more here.
Keywords: regulate autophagy; propofol; cytoprotection; anesthetics regulate ... See more keywords
BPC157 rescued NSAID-cytotoxicity via stabilizing intestinal permeability and enhancing cytoprotection.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200523180301
Abstract: The stable gastric pentadecapeptideBPC 157 protects stomach cells, maintains gastric integrity against various noxious agents such as alcohol, nonsteroidal anti-inflammatory drugs (NSAIDs), and exerts cytoprotection/adaptive cytoprotection/organoprotection in other epithelia, that is, skin, liver, pancreas, heart,… read more here.
Keywords: cytoprotection; rescued nsaid; permeability; bpc 157 ... See more keywords
Modulating Nitric Oxide: Implications for Cytotoxicity and Cytoprotection
Sign Up to like & getrecommendations! Published in 2024 at "Antioxidants"
DOI: 10.3390/antiox13050504
Abstract: Despite the significant progress in the fields of biology, physiology, molecular medicine, and pharmacology; the designation of the properties of nitrogen monoxide in the regulation of life-supporting functions of the organism; and numerous works devoted… read more here.
Keywords: system; cytoprotection; modulating nitric; implications cytotoxicity ... See more keywords
Active nNOS Is Required for Grp94-Induced Antioxidant Cytoprotection: A Lesson from Myogenic to Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23062915
Abstract: The endoplasmic reticulum (ER) chaperone Grp94/gp96 appears to be involved in cytoprotection without being required for cell survival. This study compared the effects of Grp94 protein levels on Ca2+ homeostasis, antioxidant cytoprotection and protein–protein interactions… read more here.
Keywords: required grp94; antioxidant cytoprotection; cytoprotection; grp94 induced ... See more keywords
Untargeted Metabolomics Identifies Faecal Filtrate-Derived Metabolites That Disrupt Clostridioides difficile Metabolism and Confer Gut Barrier Cytoprotection
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262211221
Abstract: Recurrent Clostridioides difficile infection (rCDI) remains a major therapeutic challenge. Although faecal microbiota transplantation (FMT) is highly effective and thought to restore microbial composition and metabolic function, the mechanisms underlying its success are not fully… read more here.
Keywords: cytoprotection; barrier; metabolism; faecal filtrate ... See more keywords
Flavonoids and Mitochondria: Activation of Cytoprotective Pathways?
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25133060
Abstract: A large number of diverse mechanisms that lead to cytoprotection have been described to date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In addition to being metabolic centers, due to… read more here.
Keywords: flavonoids mitochondria; cytoprotective pathways; cytoprotection; mitochondria activation ... See more keywords