Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202410908
Abstract: Fast twitch, type II muscle fibers are particularly prone to degradation in skeletal muscle pathologies, such as sarcopenia and muscular dystrophies. We previously showed that endogenous activation of the exercise-induced long noncoding RNA CYTOR promotes… read more here.
Keywords: chemically modified; noncoding rna; muscle; delivery ... See more keywords
Matrix stiffness-dependent regulation of immunomodulatory genes in human MSCs is associated with the lncRNA CYTOR
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2404146121
Abstract: Significance Mechanotransduction, the translation of external physical cues to internal biochemical signals, influences cellular processes and behaviors. Here, we explore such mechanisms that underlie cellular responses to environmental stiffness using a 3D, tissue-mimetic culturing platform.… read more here.
Keywords: regulation immunomodulatory; cytor; dependent regulation; stiffness dependent ... See more keywords
Long non-coding RNA (lncRNA) CYTOR promotes hepatocellular carcinoma proliferation by targeting the microRNA-125a-5p/LASP1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2024328
Abstract: ABSTRACT This study investigated the function of long non-coding RNA (lncRNA) cytoskeleton regulator RNA (CYTOR) in hepatocellular carcinoma (HCC). In HCC, the expression of CYTOR and microRNA (miR)-125a-5p were measured by quantitative real-time PCR (qRT-PCR).… read more here.
Keywords: non coding; hcc; mir 125a; rna ... See more keywords
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis
Sign Up to like & getrecommendations! Published in 2024 at "Pathogens and Disease"
DOI: 10.1093/femspd/ftae011
Abstract: Abstract Chlamydia trachomatis infection can be regulated by autophagy-related genes. LncRNA CYTOR has been proven to be involved in autophagy. In this research, we investigated the role of CYTOR in autophagy induced by C. trachomatis… read more here.
Keywords: chlamydia trachomatis; cytor; autophagy; mapk1 ... See more keywords
Hepatocyte‐derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.18234
Abstract: Liver fibrosis is characterized by the activation and transformation of hepatic stellate cells (HSCs) induced by various injury factors. The degree of liver fibrosis can be significantly improved, but persistent injury factors present a significant… read more here.
Keywords: fibrosis; stellate cells; liver fibrosis; damaged liver ... See more keywords
lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/5671809
Abstract: Periodontal ligament stem cells (PDLSCs) are considered ideal cell sources for the regeneration of periodontal and alveolar bone tissue. Cytoskeleton Regulator RNA (CYTOR), a newly discovered long noncoding RNA, has been reported to function as… read more here.
Keywords: pdlscs; osteogenic differentiation; cytor; mir 6512 ... See more keywords
The Long Noncoding RNA Cytoskeleton Regulator RNA (CYTOR)/miRNA-24-3p Axis Facilitates Nasopharyngeal Carcinoma Progression by Modulating GAD1 Expression
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/6027860
Abstract: Nasopharyngeal carcinoma (NPC) is a head and neck epithelial carcinoma that is unusually prevalent in Southeast Asia. Noncoding RNAs, including lncRNA and miRNA, and their target genes are considered vital regulators of tumorigenesis and the… read more here.
Keywords: nasopharyngeal carcinoma; progression; cytor; gad1 expression ... See more keywords
The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0860-7
Abstract: BackgroundLong non-coding RNAs (lncRNAs) function as key molecules in cancer progression. The lncRNA CYTOR plays oncogenic roles in multiple types of cancer, yet the detailed molecular mechanisms of those roles remain unknown. The aim of… read more here.
Keywords: ncl sam68; crc; cancer; cytor ... See more keywords
UPF1 alleviates the progression of glioma via targeting lncRNA CYTOR.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19567
Abstract: OBJECTIVE To uncover the role of UPF1 in alleviating the progression of glioma via targeting long non-coding RNA (lncRNA) CYTOR and underlying mechanism. PATIENTS AND METHODS A total of 30 glioma tissues surgically resected from… read more here.
Keywords: progression glioma; glioma; glioma tissues; glioma via ... See more keywords
Long Noncoding RNA Cytoskeleton Regulator RNA Suppresses Apoptosis in Hepatoma Cells by Modulating the miR-125a-5p/HS1-Associated Protein X-1 Axis to Induce Caspase-9 Inactivation.
Sign Up to like & getrecommendations! Published in 2023 at "Gut and liver"
DOI: 10.5009/gnl210572
Abstract: Background/Aims The involvement of long noncoding RNAs in the carcinogenesis of hepatocellular carcinoma (HCC) has been well documented by substantial evidence. However, whether cytoskeleton regulator RNA (CYTOR) could affect the progression of HCC remains unclear.… read more here.
Keywords: cell; apoptosis; hcc cells; mir 125a ... See more keywords