Efficient Editing of Silver Nanoclusters by Changing Simply One Cytosine in a DNA Template
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DOI: 10.1002/cbic.202000640
Abstract: DNA with genetic information was edited to regulate and repair the structure and function of a protein. In DNA nanotechnology, DNA with programmable information can be designed to edit the fluorescence intensity and emissive colors… read more here.
Keywords: dna; template; silver nanoclusters; cytosine dna ... See more keywords
Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity
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DOI: 10.1038/s41588-018-0061-8
Abstract: Methylation at the 5 position of cytosine in DNA (5meC) is a key epigenetic mark in eukaryotes. Once introduced, 5meC can be maintained through DNA replication by the activity of ‘maintenance’ DNA methyltransferases (DNMTs). Despite… read more here.
Keywords: methylation; dna; cytosine dna; dna methylation ... See more keywords
RNAi is a critical determinant of centromere evolution in closely related fungi
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DOI: 10.1073/pnas.1713725115
Abstract: Significance The “centromere paradox” refers to rapidly evolving and highly diverse centromere DNA sequences even in closely related eukaryotes. However, factors contributing to this rapid divergence are largely unknown. Here, we identified large regional, LTR… read more here.
Keywords: closely related; evolution; rnai; cytosine dna ... See more keywords
Recruitment of histone modifications to assist mRNA dosage maintenance after degeneration of cytosine DNA methylation during animal evolution.
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DOI: 10.1101/gr.221739.117
Abstract: Following gene duplication, mRNA expression of the duplicated gene is reduced to maintain mRNA dosage. In mammals, this process is achieved with increased cytosine DNA methylation of the promoters of duplicated genes to suppress transcriptional… read more here.
Keywords: mrna dosage; cytosine dna; dna methylation; dna ... See more keywords