Targeted Bisulfite Sequencing Using the SeqCap Epi Enrichment System.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7481-8_20
Abstract: Cytosine methylation has been shown to have a role in a host of biological processes. In mammalian biology these include stem cell differentiation, embryonic development, genomic imprinting, inflammation, and silencing of transposable elements. Given the… read more here.
Keywords: bisulfite sequencing; cytosine methylation; seqcap epi; biology ... See more keywords
Enzymatic Approaches for Profiling Cytosine Methylation and Hydroxymethylation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular metabolism"
DOI: 10.1016/j.molmet.2021.101314
Abstract: BACKGROUND In mammalian genomes, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome. The canonical epigenetic mark is 5-methylcytosine (5mC), but oxidized versions of 5mC including… read more here.
Keywords: methylation; dna; enzymatic approaches; profiling cytosine ... See more keywords
Cytosine methylation regulates DNA bendability depending on the curvature
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc07115g
Abstract: Cytosine methylation plays an essential role in many biological processes, such as nucleosome inactivation and regulation of gene expression. The modulation of DNA mechanics may be one of the regulatory mechanisms influenced by cytosine methylation.… read more here.
Keywords: methylation; cytosine methylation; depending curvature; mechanics ... See more keywords
Manipulation of cytosine methylation does not remove latitudinal clines in two invasive goldenrod species in Central Europe
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Ecology"
DOI: 10.1111/mec.15722
Abstract: Invasive species frequently differentiate phenotypically in novel environments within a few generations, often even with limited genetic variation. For the invasive plants Solidago canadensis and S. gigantea, we tested whether such differentiation might have occurred… read more here.
Keywords: methylation; latitudinal clines; cytosine methylation; central europe ... See more keywords
Sugarcane mosaic virus mediated changes in cytosine methylation pattern and differentially transcribed fragments in resistance-contrasting sugarcane genotypes
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DOI: 10.1371/journal.pone.0241493
Abstract: Sugarcane mosaic virus (SCMV) is the causal agent of sugarcane mosaic disease (SMD) in Brazil; it is mainly controlled by using resistant cultivars. Studies on the changes in sugarcane transcriptome provided the first insights about… read more here.
Keywords: methylation; changes cytosine; cytosine methylation; sugarcane mosaic ... See more keywords
The Dynamic Regulation of G-Quadruplex DNA Structures by Cytosine Methylation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052407
Abstract: It is well known that certain non B-DNA structures, including G-quadruplexes, are key elements that can regulate gene expression. Here, we explore the theory that DNA modifications, such as methylation of cytosine, could act as… read more here.
Keywords: dynamic regulation; dna; dna structures; cytosine methylation ... See more keywords