Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "iScience"
DOI: 10.1016/j.isci.2021.103536
Abstract: Summary Ataxin-2 (Atx2) is a highly conserved RNA binding protein. Atx2 undergoes polyglutamine expansion leading to amyotrophic lateral sclerosis (ALS) or spinocerebellar ataxia type 2 (SCA2). However, the physiological functions of Atx2 in neurons remain… read more here.
Keywords: ataxin essential; cytoskeletal dynamics; cytoskeletal; essential cytoskeletal ... See more keywords
Investigation of the Cytoskeletal Dynamics during Spiral Cleavage
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.125
Abstract: Spiral cleavage is the ancestral developmental mode within the Spiralia. It covers a period of the early development characterized by asymmetric divisions with alternating division angles giving the embryo a spiral looking appearance. The position… read more here.
Keywords: investigation cytoskeletal; cleavage; division; cytoskeletal dynamics ... See more keywords
The role of LRRK2 in cytoskeletal dynamics.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Society transactions"
DOI: 10.1042/bst20180469
Abstract: Leucine-rich repeat kinase 2 (LRRK2), a complex kinase/GTPase mutated in Parkinson's disease, has been shown to physically and functionally interact with cytoskeletal-related components in different brain cells. Neurons greatly rely on a functional cytoskeleton for… read more here.
Keywords: lrrk2 cytoskeletal; role lrrk2; cytoskeletal dynamics;
Live Imaging of Cytoskeletal Dynamics in Embryonic Xenopus laevis Growth Cones and Neural Crest Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot104463
Abstract: The cytoskeleton is a dynamic, fundamental network that not only provides mechanical strength to maintain a cell's shape but also controls critical events like cell division, polarity, and movement. Thus, how the cytoskeleton is organized… read more here.
Keywords: cones neural; growth cones; cytoskeletal dynamics; neural crest ... See more keywords
Identification of ARMH4 and WIPF3 as human podocyte proteins with potential roles in immunomodulation and cytoskeletal dynamics
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280270
Abstract: The podocyte is a specialized cell type critically involved in maintaining the selective filtration barrier of the kidney. Podocytes are primary or secondary targets for a multitude of kidney diseases. Despite intense investigation, the transcriptome… read more here.
Keywords: podocyte; human kidneys; overexpression; armh4 wipf3 ... See more keywords
SARM1 Suppresses Axon Branching Through Attenuation of Axonal Cytoskeletal Dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.726962
Abstract: Axon branching is a fundamental aspect of neuronal morphogenesis, neuronal circuit formation, and response of the nervous system to injury. Sterile alpha and TIR motif containing 1 (SARM1) was initially identified as promoting Wallerian degeneration… read more here.
Keywords: axon branching; formation; cytoskeletal dynamics; sensory neurons ... See more keywords
Tracking of Endothelial Cell Migration and Stiffness Measurements Reveal the Role of Cytoskeletal Dynamics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010568
Abstract: Cell migration is a complex, tightly regulated multistep process in which cytoskeletal reorganization and focal adhesion redistribution play a central role. Core to both individual and collective migration is the persistent random walk, which is… read more here.
Keywords: microscopy; cytoskeletal dynamics; stiffness; migration ... See more keywords